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A High-Efficiency Two-Stroke Engine Concept: The Boosted Uniflow Scavenged Direct-Injection Gasoline(BUSDIG) Engine with Air Hybrid Operation Review

Xinyan Wang, Hua Zhao

Engineering 2019, Volume 5, Issue 3,   Pages 535-547 doi: 10.1016/j.eng.2019.03.008

Abstract:

A novel two-stroke boosted uniflow scavenged direct-injection gasoline (BUSDIG) engine has been proposedare summarized to highlight the progress of the development of the proposed two-stroke BUSDIG enginescavenging performance and produce sufficient incylinder flow motions for the fuel/air mixing process in the two-strokeBUSDIG engine, the engine bore/stroke ratio, intake scavenge port angles, and intake plenum design wereThe results showed that a maximum brake thermal efficiency of 47.2% can be achieved for the two-stroke

Keywords： Two-stroke engine     Uniflow scavenging     Engine design     Engine simulation     Scavenging performance     Thermal    

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Control of homogeneous charge compression ignition combustion in a two-cylinder gasoline direct injectionengine with negative valve overlap

WANG Zhi, WANG Jianxin, SHUAI Shijin, MA Qingjun, TIAN Guohong

Frontiers in Energy 2007, Volume 1, Issue 3,   Pages 311-315 doi: 10.1007/s11708-007-0045-3

Abstract: In this paper, HCCI combustion was studied in a two-cylinder gasoline direct injection (GDI) engine withA two-stage gasoline direct injection strategy combined with negative valve overlap was used to controlThe gasoline engine could be operated in HCCI combustion mode at a speed range of 800–2 200 r/min andThe engine fuel consumption is below 240 g/(kW

Keywords： Homogeneous     control     combustion     consumption     extension    

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Interactions between remote ischemic conditioning and post-stroke sleep regulation

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 867-876 doi: 10.1007/s11684-021-0887-9

Abstract: Sleep disturbances are common in patients with stroke, and sleep quality has a critical role in the onsetand outcome of stroke.Thus, exploring a therapy suitable for patients with stroke and sleep disturbances is imperative.ischemic conditioning can reduce the ischemic size of the brain, improve the functional outcome of strokesleep regulation, a causal relationship was proposed between remote ischemic conditioning and post-stroke

Keywords： remote ischemic conditioning     sleep regulation     stroke    

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Genetics of ischemic and hemorrhagic stroke in Chinese population

Wei-Li ZHANG MD, PhD, Ru-Tai HUI MD, PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 21-28 doi: 10.1007/s11684-010-0013-x

Abstract: Stroke is a major cause of adult death and disability worldwide.Genetic influences are likely to be polygenic with small effect sizes, and stroke itself consists ofIn addition, various ethnic populations may have different stroke risk, such as Asian race.The reasons for high risk of stroke among the Chinese, especially hemorrhagic stroke, remain unknown.The combined effects of multiple susceptibility genes for stroke risk are also summarized.

Keywords： genetics     ischemic stroke     hemorrhagic stroke     association study    

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EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 740-749 doi: 10.1007/s11684-020-0794-5

Abstract: Stroke is one of the most serious diseases that threaten human life and health.New strategies for motor rehabilitation after stroke are undergoing exploration.BCI) and functional electrical stimulation (FES) technologies, for limb motor function recovery after strokeWe conducted clinical trials (including controlled trials) in 32 patients with chronic stroke.

Keywords： interface     functional electrical stimulation     electroencephalogram     laterality coefficient     chronic stroke    

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Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Frontiers of Medicine doi: 10.1007/s11684-023-1041-7

Abstract: An increasing number of studies have identified a complex relationship between COVID-19 and stroke, althoughSevere COVID-19 may be associated with an increased risk of stroke and increase the rates of disabilityand mortality, posing a serious challenge to acute stroke diagnosis, treatment, and care.This review aims to provide an update on the influence of COVID-19 itself or vaccines on stroke, includingarterial stroke (ischemic stroke and hemorrhagic stroke) and venous stroke (cerebral venous thrombosis

Keywords： SARS-CoV-2     ischemic stroke     stroke     hemorrhagic stroke     cerebral venous thrombosis     vaccination    

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Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 20-29 doi: 10.1007/s11684-014-0371-x

Abstract:

Ischemic stroke is a focal cerebral insult that often leads to many adverse neurological complicationsThe prevalence of stroke is increasing throughout the world, while the efficacy of current pharmacologicalumbilical cord mesenchymal stem cells (hUC-MSCs) has shown great possibility to restore function after strokeThis review article provides an update role of hUC-MSCs implantation in the treatment of ischemic stroke

Keywords： cellular therapy     transplantation     human umbilical cord     mesenchymal stem cells     ischemic stroke    

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Stroke prevention: an update

Marie-Germaine Bousser

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 22-34 doi: 10.1007/s11684-012-0178-6

Abstract:

Stroke is a personal, familial, and social disaster.The burden of stroke is likely to increase given the aging of the population and the growing incidencePrevention of stroke includes—as for all other diseases—a “mass approach” aimingcombines a vascular risk factor modification and various treatments addressing the specific subtypes of strokeThere is a growing awareness of the huge evidence-to-practice gap that exists in stroke prevention largely

Keywords： stroke     prevention     vascular risk factors     cerebral infarction     cerebral hemorrhage     anti-thrombotic drugs    

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A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment

Yufeng Zhao, Bo Liu, Liyun He, Wenjing Bai, Xueyun Yu, Xinyu Cao, Lin Luo, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 432-439 doi: 10.1007/s11684-017-0511-1

Abstract:

Traditional Chinese patent medicines are widely used to treat stroke because it has good efficacyManifold Ranking is employed to develop the aid-decision model of traditional Chinese patent medicines for strokeFirst, 115 stroke patients from three hospitals are recruited in the cross-sectional survey.indicators are explored to characterize the population feature of traditional Chinese patent medicines for strokeThird, the aid-decision model of traditional Chinese patent medicines for stroke treatment is constructed

Keywords： traditional Chinese patent medicines     stroke     aid decision     data mining     manifold ranking    

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EEG controlled neuromuscular electrical stimulation of the upper limb for stroke patients

Hock Guan TAN, Cheng Yap SHEE, Keng He KONG, Cuntai GUAN, Wei Tech ANG

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 1,   Pages 71-81 doi: 10.1007/s11465-011-0207-1

Abstract: describes the Brain Computer Interface (BCI) system and the experiments to allow post-acute (<3 months) stroketo regulate their -rhythm EEG to operate the BCI to trigger NMES of the wrist/finger. 6 post-acute stroke

Keywords： brain computer interface     neuromuscular electrical stimulation     stroke     musculoskeletal modeling    

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Status of hyperhomocysteinemia in China: results from the China Stroke High-risk Population Screening

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 903-912 doi: 10.1007/s11684-021-0871-4

Abstract: HHYP was an independent predictor of stroke with an adjusted odds ratio of 1.752 (95% CI 1.338–2.105)

Keywords： homocysteine     hyperhomocysteinemia     H-type hypertension     Chinese    

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Design and modeling of a free-piston engine generator

Frontiers in Energy   Pages 811-821 doi: 10.1007/s11708-022-0848-2

Abstract: Free-piston engine generators (FPEGs) can be applied as decarbonized range extenders for electric vehiclesThe parameter-decoupling approach first divides the FPEG into three parts: a two-stroke engine, an integratedEmpirical equations were adopted to design the engine and scavenging pump, while special considerations

Keywords： free-piston engine generator     linear permanent magnet synchronous machine     system design     numerical model    

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proteomics revealed extensive microenvironmental changes after stem cell transplantation in ischemic stroke

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 429-441 doi: 10.1007/s11684-021-0842-9

Abstract: The local microenvironment is essential to stem cell-based therapy for ischemic stroke, and spatiotemporalHowever, relevant studies on microenvironmental changes were mainly confined in the acute phase of strokeaimed to investigate the microenvironmental changes in the subacute and chronic phases of ischemic strokeinvestigate the protein expression profiles in iPSCs-transplanted brain in the subacute and chronic phases of strokeTaken together, our study indicated that iPSCs have a positive therapeutic effect in ischemic stroke

Keywords： ischemic stroke     microenvironment     induced pluripotent stem cells (iPSCs)     positron emission tomography    

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Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 420-426 doi: 10.1007/s11684-019-0688-6

Abstract: on the mechanisms of blood—brain barrier (BBB) alteration and autoimmune response in acute ischemic strokerelationship between the severity of immunobiochemical changes and clinical outcome of acute ischemic strokeIschemic stroke is accompanied by aseptic inflammation, which alters the brain tissue and exposes theGlymphatic system function is altered and jeopardized both in hemorrhagic and ischemic stroke types.At the same time, the stroke-induced immune activation may promote reparation phenomena in the brain.

Keywords： stroke     blood–brain barrier     autoimmunity     innate immunity     inflammation     cell death    

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Title Author Date Type Operation

A High-Efficiency Two-Stroke Engine Concept: The Boosted Uniflow Scavenged Direct-Injection Gasoline(BUSDIG) Engine with Air Hybrid Operation

Xinyan Wang, Hua Zhao

Journal Article

Corrigendum to ‘‘A High-Efficiency Two-Stroke Engine Concept: The Boosted Uniflow Scavenged Direct-InjectionGasoline (BUSDIG) Engine with Air Hybrid Operation” [Engineering 5 (2019) 535–547]

Xinyan Wang, Hua Zhao

Journal Article

Control of homogeneous charge compression ignition combustion in a two-cylinder gasoline direct injectionengine with negative valve overlap

WANG Zhi, WANG Jianxin, SHUAI Shijin, MA Qingjun, TIAN Guohong

Journal Article

Interactions between remote ischemic conditioning and post-stroke sleep regulation

Journal Article

Genetics of ischemic and hemorrhagic stroke in Chinese population

Wei-Li ZHANG MD, PhD, Ru-Tai HUI MD, PhD,

Journal Article

EEG-controlled functional electrical stimulation rehabilitation for chronic stroke: system design and

Journal Article

Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Journal Article

Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Journal Article

Stroke prevention: an update

Marie-Germaine Bousser

Journal Article

A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment

Yufeng Zhao, Bo Liu, Liyun He, Wenjing Bai, Xueyun Yu, Xinyu Cao, Lin Luo, Peijing Rong, Yuxue Zhao, Guozheng Li, Baoyan Liu

Journal Article

EEG controlled neuromuscular electrical stimulation of the upper limb for stroke patients

Hock Guan TAN, Cheng Yap SHEE, Keng He KONG, Cuntai GUAN, Wei Tech ANG

Journal Article

Status of hyperhomocysteinemia in China: results from the China Stroke High-risk Population Screening

Journal Article

Design and modeling of a free-piston engine generator

Journal Article

proteomics revealed extensive microenvironmental changes after stem cell transplantation in ischemic stroke

Journal Article

Autoimmunity in acute ischemic stroke and the role of blood—brain barrier: the dark side or the light

Nikolay V. Tsygan, Alexandr P. Trashkov, Igor V. Litvinenko, Viktoriya A. Yakovleva, Alexandr V. Ryabtsev, Andrey G. Vasiliev, Leonid P. Churilov

Journal Article